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- The formation of cytosolic lipid droplets (LD) incorporating neutral lipids is a common adaptation to cellular stress triggered by factors such as redox imbalance, excessive free fatty acids or nutrient starvation [45,49]
- In contrast, NHEJ repairs DSBs by connecting two free chromosome ends together with little requirement for sequence homology, which leads to a high frequency of chromosome misarrangements (1)
- In addition, our model has a unique parameter (experiments
- Thus, we demonstrated recently, after in vivo transplantation of L428 cells in different phases of antigen acquisition, how the design of TMMs evolves, with high telomerase expression in the tiny CD30?/CD15? cells, and intensifying expression of the ALT profile until acquisition of the HRS cell phenotype, with predominant PML physiques, low telomerase manifestation [56], and the current presence of tumor cells without TMM staining
- [PMC free content] [PubMed] [Google Scholar] [37] Rao CV, Wolf DM and Arkin AP, Control, tolerance and exploitation of intracellular noise, Character, 420 (2002), 231
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