The virulence of the novel coronavirus in human milk is not confirmed, while significant amounts of exclusive antibodies are

The virulence of the novel coronavirus in human milk is not confirmed, while significant amounts of exclusive antibodies are. ConclusionLactation in the context of COVID-19 has shown greater benefits than risks of vertical transmission. of the present study. The research took place in the period from March 27 to April 2, 2021. Synthesis of the dataBreast milk has diverse benefits for both the nursing mother and the infant. The presence of viral RNA by real-time polymerase chain reaction (RT-PCR) in milk from disease-positive mothers has been detected in a few cases, and infant infections in these conditions suggest oral transmission of maternal or third-party origin. The virulence of the novel coronavirus in human milk is not confirmed, while significant amounts of unique antibodies are. ConclusionLactation in the context of COVID-19 has shown greater benefits than risks of vertical transmission. Therefore, it should be motivated when possible. Keywords:COVID-19, SARS-CoV-2 contamination, breastfeeding, vertical infectious disease transmission, immunology == Resumo == ObjetivoO presente artigo procura consolidar os conhecimentos existentes sobre o aleitamento materno durante a pandemia do SARS-CoV-2. Fonte de dadosForam analisados os artigos de 2020 e 2021 recolhidos dos bancos de dados PubMed, CAPES, Biblioteca Virtual de Sade, Google Scholar, SciELO e bases de dados UpToDate. Livros e documentos governamentais publicados na ltima dcada (20102020) tambm foram consultados. Seleo de estudosDezesseis obras foram utilizadas no presente estudo. A data de publicao e MAC13243 discusso sobre a transmisso do SARS-CoV-2 atravs do leite materno foram os critrios de incluso. Assim, foram excludos os artigos que continham informaes repetidas ou sem relevncia para a produo. Coleta de dadosPara a preparao do presente estudo, foram realizadas leituras crticas e sntese das principais informaes obtidas sobre o tema. A pesquisa ocorreu no perodo de 27 de maro a 2 de abril de 2021. Sntese dos dadosO leite materno tem diversos benefcios tanto para a me quanto para o lactente. A presena de RNA viral por reao em cadeia de polimerase em tempo real (RT-PCR, na sigla em ingls) no leite de mes positivas foi detectada em alguns casos, e as infeces infantis nestas condies sugerem transmisso oral de origem materna ou de terceiros. A virulncia do novo coronavrus no leite humano Edn1 no est confirmada, enquanto quantidades significativas de anticorpos exclusivos sim. ConclusoA lactao no contexto da COVID-19 mostrou maiores benefcios do que os riscos de MAC13243 transmisso vertical. Por conseguinte, deve ser encorajada sempre que possvel. Palavras-chave:COVID-19, infeco por SARS-CoV-2, aleitamento materno, transmisso vertical de doenas infecciosas, imunologia == Introduction == In the epilogue of December 2019 and in MAC13243 the introduction of the year 2020, the world witnessed the rise of severe acute respiratory syndrome (SARS) caused by a new variant of coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which was declared in January 2020 by the World Health Business (WHO) as an epidemiological pandemic situation. This etiologic agent was responsible for naming a new disease classification known as Coronavirus disease 2019 (COVID-19), which is considered a public health emergency of international concern (EPII). Moreover, this health condition has become one of the main causes of increased mortality rates, as well as of increased efforts by the most diverse centers of medical practice and research in attempts to understand the disease and its therapeutic approach.1 In general terms, the clinical manifestations of COVID-19 are variable, a reality that demands great attention from healthcare teams. The most common symptoms of the disease are typical of a flu-like syndrome, and involve cough, fever, dyspnea, myalgia, and, in some cases, abdominal pain and diarrhea. So far, it has been observed that the disease most frequently affects adults and the elderly, although it is already known that pregnant women, mothers, newborns, and children can also develop it in its aggravating form. However, it is known that this expressivity of these same aspects can be mild and even asymptomatic, although many cases can evolve to severe acute respiratory syndrome, septic shock, and multiple organ failure.12In this perspective, the clinical evolution of the disease can be associated to the degree of inflammatory response in the organism of the infected individual, since the higher MAC13243 the degree, the greater the tissue damage and, consequently, the functional compromise of the affected regions.3 Regarding the transmissibility of the virus, it is known that it enters the body mainly through inhalation of infected air. Moreover, it can enter the body due to contact of the individual with contaminated surfaces (food packaging and.