The explanation for being familiar with this appearance is that evaluating IgG4 deposition in a cost-effective manner with traditional DIF is of diagnostic value, especially in undiagnosed clinically active smoldering pemphigus cases despite this treated with inadequate immunosuppression and thus having equivocal results of serum testing with ELISA techniques and DIF testing for just IgG and C3 deposition, as it enables the detection of Th2-mediated phenomena characteristic for the active stage of pemphigus [5]

The explanation for being familiar with this appearance is that evaluating IgG4 deposition in a cost-effective manner with traditional DIF is of diagnostic value, especially […]

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